1 2 3 4 5 6 7 8 9 10 11 12

8


reversible/irreversible

aluminium may be

due

to

formation

of

aluminium complex. Aluminium

has

high

affinity

for

proteins,

carbohydrates and polynucleotides and may exist as reversible

macromolecular

complex

of

cation/polyanion

[5].

If

the

cation/polyanion ratio exceeds a threshold value, irreversible

complex

can

be

formed

giving

rise

to

inhibitory

effect

of


and


of

aluminium. Polynuclear ions

can

produce


Though

membrane

changes

aggregate

biomolecules

[4].

the

formation

reversible/irreversible

complex

can

be

postulated

to

explain

biphasic effect of aluminium, it remains to be elucidated in


detail.